Associate Professor in Clinical Pharmacology und Anaesthesia, The Royal Veterinary College London
Professor Ludovic Pelligand Ludovic is professor of Veterinary Anaesthesia and Clinical Pharmacology and co-head of the anaesthesia /analgesia service - a team strong of 26 members, operating in the different RVC referral hospitals. Ludovic graduated from the École Nationale Vétérinaire d'Alfort (Paris, France) in 2001, where he completed a two-year small animal internal medicine internship. He then completed a 3-year anaesthesia residency at the Royal Veterinary College (RVC), London, UK where he gained his European Diploma of Veterinary Anaesthesia and Anaesthesia (Dip. ECVAA) in 2006. Ludovic completed his pharmacology PhD at the RVC in 2010 on the roles of cyclooxygenase (COX) isoenzymes in the regulation of inflammation and the renal function in the cat (supervised by Professor Jonathan Elliott and Professor Peter Lees and Dr. Jon King, Novartis Animal Health). Ludovic embarked on a post-doctoral appointment at the RVC and gained the European Diploma in Veterinary Pharmacology and Toxicology (Dip. ECVPT) in 2014. Ludovic has been back in the clinics as a senior anaesthetist since the end of his PhD. Clinician at heart, he thrives running the busy service, teaching students and anaesthesia residents and finding innovative solutions to deal with anaesthetic challenges. Ludovic is a principal investigator who promotes the use of mathematical modelling and pharmacometrics (i.e. the PK/PD approach) to help resolve clinical questions at the level of the individual animal or for more global questions, as in the field of antimicrobial clinical breakpoints. Ludovic is in the steering committee of VetCAST, the veterinary section of the European Committee on Antimicrobial Susceptibility Testing (EUCAST). He is actively involved in the European Network for Optimization of Veterinary Antimicrobial Treatment (ENOVAT) and in the H2020 project: Alternatives to Veterinary Antibiotics (AVANT). Ludovic is the leader of the work-package on antimicrobials in the One Health Poultry Hub (onehealthpoultry.org), where he coordinates a network to detect antimicrobial residues in chicken production in India, Bangladesh, Sri Lanka and Vietnam. His other main research interests is analgesics pharmacology. He is developing research programs in pharmacology and pain management (acute and chronic), particularly in the area of mathematical modeling of the effects of NSAIDs, opioids, alpha-2 agonists, gabapentinoids and cannabinoids in cats, dogs, horses, ruminants but also more exotic species such as emus or salamanders. Ludovic collaborates in his research with colleagues from the RVC but has also established solid research or business relationships with external companies as Transpharmation, Triveritas, CEVA, and Zoetis. Ludovic is striving to expand the RVC analytical laboratory to support veterinary a therapeutic drug monitoring service and drug development schemes in collaboration with deltaDOT Ltd. He successfully marketed a iohexol clearance test for clinical monitoring of glomerular filtration rate (GFR) in dogs and cats. Ludovic also an active member of several international committees, such as the Therapeutic Guidelines Group of the World Small Animal Veterinary Association, the Comité Analyse et Maîtrise du Risque, Societe Francaise Anesthesie et Reanimation (SFAR) and the Animal Health Modelling and Simulation Society. He has also provided expert advice to CVMP/EMA in the field of clinical breakpoints for antimicrobials.